Structural Genomics Consortium

Recent papers from Structural Genomics Consortium

1. Enabling Computational Exploration of an Expanding Academic Chemistry SpaceJournal of Chemical Information and Modeling · 2026
2. HAP40 functions as a proteostasis regulator by controlling huntingtin interactions and its release into the extracellular spaceProceedings of the National Academy of Sciences · 2026
3. The pan-African natural products library compounds oleanolic acid, poinsettifolin B, and rhuschalcone III disrupt SARS-CoV-2 spike-host ACE2 interactions and SARS-CoV-2 replicationBMC Pharmacology and Toxicology · 2026
4. CDK4/6 inhibition radiosensitizes p16-negative squamous cell carcinomas of the aerodigestive tract via cell cycle arrestInternational Journal of Radiation Biology · 2026
5. PRMT7 restricts CD8+ T cells expansion via the NF-ΚB pathwayNature Communications · 2026
6. A chromatin-informed transcriptional regulatory framework to stratify patients and guide therapy selection in triple-negative breast cancerNature Communications · 2026
7. Hepatocyte growth factor activator inhibitor-2 rapidly inactivates airway-expressed human Type II Transmembrane Serine ProteasesJournal of Biological Chemistry · 2026
8. Integrated in silico approaches for the identification of promising dual-target inhibitors of Mycobacterium tuberculosis DprE1 and InhA enzymesIn Silico Research in Biomedicine · 2026
9. EUbOPEN Data Management Plan2026
10. In vitro multi-organ invasion model for exploring cardiac resistance to cancer metastasisNature Communications · 2026
11. MANGO‐“Fruitcage”: A Conditional Photocage Utilizing a Fluorescence Light‐Up AptamerAdvanced Optical Materials · 2026
12. Fragility of precision: resistance to mutant p53 reactivationSignal Transduction and Targeted Therapy · 2026
13. An Atlas of Short Linear Motif-Mediated Human Protein-Protein Interactions2026
14. Active learning for the accelerated discovery of complex concentrated NiCoCr alloys in additive manufacturingnpj Advanced Manufacturing · 2026
15. Structure‐Based Design, Synthesis, and Evaluation of Novel Ponatinib Derivatives With a Significantly Altered Selectivity ProfileChemMedChem · 2026
16. Lessons From Drug Discovery for Cryoprotective Agent Design: An AI‐Oriented PerspectiveAdvanced Science · 2026
17. Changes in Genetic Contributions to ASD and ADHD by Year of DiagnosisJAMA Psychiatry · 2026
18. Automated synthesis of InSb quantum dots with improved batch-to-batch reproducibility via kinetically matched co-reductionNature Communications · 2026
19. High-throughput protein target mapping enables accelerated bioactivity discovery for ToxCast and PFAS compoundsProceedings of the National Academy of Sciences · 2026
20. Mapping the global digital discourse on nutraceuticals: a two-year hashtag analysis of the X platform (formerly T witter)Animal Science Papers and Reports · 2026