Shanghai Center For Bioinformation Technology

Recent papers from Shanghai Center For Bioinformation Technology

1. A Living Multi‐Omics PDX Biobank of High‐Risk Sarcomas Reveals ecDNA‐Driven Oncogene Amplification in Osteosarcoma and Enables Preclinical Precision OncologyAdvanced Science · 2026
2. Sleep quality is associated with gut microbiome signatures of hyperuricemia in Chinese elderly adults: a community-based case–control studyBMC Microbiology · 2026
3. Bifunctional Phagocytic Synapse Enhancers Remodel the Tumor Microenvironment to Overcome ImmunosuppressionCancer Research · 2026
4. Macrophage lipid efflux regulates the tumour microenvironment in early‐stage lung adenocarcinomaClinical and Translational Discovery · 2026
5. Two essential criteria for transcription factor footprint discovery using V-plotMolecular Systems Biology · 2026
6. Bio-OS: An Integrated Cloud-native Environment for Data-Intensive Biomedical ResearchGenomics Proteomics & Bioinformatics · 2026
7. Automated limb motor assessment in Parkinson’s disease via a time-frequency state-space modelnpj Digital Medicine · 2026
8. Tumor-Derived Model Biobanks in China: Current Status and Future ChallengesBiopreservation and Biobanking · 2026
9. Amplicon-based DNA and RNA unified NGS for enhanced fusion variant detection in suboptimal real-world NSCLC FFPE specimensTranslational Oncology · 2026
10. IDEAL-Age: an interpretable deep learning framework for single-cell resolution profiling of immunological agingGenome biology · 2026
11. RBFOX3 is associated with neuronal-like phenotypic transition in recurrent glioblastomaBMC Cancer · 2026
12. SAA1 Promotes Pro-inflammatory Macrophage-mediated Bone Invasion in Silent Corticotroph AdenomasGenomics Proteomics & Bioinformatics · 2026
13. An integrative epigenomic and single-cell framework identifies a prognostic DNA methylation risk score and ZNF638 silencing in urothelial carcinomaJournal of Translational Medicine · 2026
14. Oral microbiome modulation mitigates hyperglycemia exacerbation in gestational diabetes mellitusNature Communications · 2026
15. Deep learning in tumour genomics: from multi-omics integration to precision oncologyOpen Biology · 2026
16. In situ generation of proinflammatory CAR macrophages via mRNA-TLR agonist co-delivery for triple-negative breast cancer immunotherapyJournal for ImmunoTherapy of Cancer · 2026
17. Echocardiography-based intelligent diagnosis and risk stratification management for tetralogy of FallotEBioMedicine · 2026
18. Elisrasib (D3S-001), a next-generation GDP-bound KRAS G12C inhibitor, as first-line therapy for KRAS G12C mutation–positive non–small cell lung cancer (NSCLC).Journal of Clinical Oncology · 2026
19. Identification and phylogenetic analysis of seven Brucella abortus strains in Zhejiang, ChinaFrontiers in Cellular and Infection Microbiology · 2026
20. An integrated analysis of SLC7A11 as a pan-cancer immunotherapeutic biomarker with experimental validation of its regulation by miR-148b-3p in breast cancerFrontiers in Immunology · 2026