Lieber Institute for Brain Development

Recent papers from Lieber Institute for Brain Development

1. Three dimensional reconstruction of the human nucleus accumbens reveals topographic organization and molecular heterogeneity of D1-islands across the anterior posterior axis2026
2. The child opportunity index and developmental outcomes in early childhoodFrontiers in Public Health · 2026
3. The psychiatric risk gene CACNA1C encodes distinct full-length isoforms in human brain, heart and aortaMolecular Psychiatry · 2026
4. Angiotensin-Converting Enzyme in Patients With Early-Stage PsychosisJAMA Psychiatry · 2026
5. Reproducible human reward imaging phenotypes exhibit differential sensitivity to dopamine D2 receptor antagonismNature Communications · 2026
6. Association Between Age-Dependent DNA Methylation Changes at FKBP5 Enhancer Sites and Increased Cortical Gene Expression in SchizophreniaAmerican Journal of Psychiatry · 2026
7. Disentangling white matter correlates of symptom severity and general impairment in early psychosisMolecular Psychiatry · 2026
8. The therapeutic potential of COMT inhibition: cognition and beyondMolecular Psychiatry · 2026
9. Schizophrenia Beyond Genome-Wide Association Studies: It’s About TimeAmerican Journal of Psychiatry · 2026
10. Protein thiol alterations drive pathologic liquid–liquid phase separation in the aging brainNature Structural & Molecular Biology · 2026
11. Profiling miRNAs Involved in Human Oligodendrocyte Precursor Cell Differentiation and MaturationCells · 2026
12. Characterization of Astrocyte Density in the Pitt–Hopkins Syndrome Mouse Model of Autism Spectrum DisorderNeuroglia · 2026
13. Analysis of gene co-expression connectivity dynamics implicates aberrant neuron-oligodendroglia interactions in schizophreniaNature Communications · 2026
14. Molecular impact of nicotine and smoking exposure on the developing and adult mouse brainAddiction Neuroscience · 2026
15. In the Search for Suicide Signatures, Phenotype MattersTranslational Psychiatry · 2026
16. Post-weaning social isolation increases reward-seeking behavior in micePhysiology & Behavior · 2026
17. BDNF-DT and BDNF-AS-DT: novel genes in the BDNF locusMolecular Psychiatry · 2026
18. Transcriptional Response to Chronic Long‐Access Fentanyl Self‐Administration in Rat Habenula and AmygdalaAddiction Biology · 2026
19. Heterogeneous responses to memantine in Alzheimer's disease: A precision medicine approach using iPSC modelsAlzheimer s & Dementia Translational Research & Clinical Interventions · 2026
20. Glutamate carboxypeptidase II activation in astrocytes mediates glymphatic impairment and cognitive vulnerability in the aging brain following surgeryAlzheimer s & Dementia · 2026