Syngene International (India)

Recent papers from Syngene International (India)

1. Visible-Light Photoredox Catalysis Enabled Triazole Annulation of Azidophilic Michael AcceptorsThe Journal of Organic Chemistry · 2026
2. Application of microdialysis and modelling approaches to predict drug concentration at the site of actionIndian Journal of Physiology and Pharmacology · 2026
3. Nitrile-Based Inhibitors Targeting both SARS-CoV-2 Main Protease and Human Cathepsin LACS Medicinal Chemistry Letters · 2026
4. Diastereoselective Synthesis of a Medicinally Significant Cis −1,1,3‐Trisubstituted Cyclopentane Derivative through Epoxide Ring OpeningEuropean Journal of Organic Chemistry · 2026
5. Discovery ofPyrazole-Containing RGD Mimics with Anti-FibroticEfficacy in the Unilateral Ureteral Obstruction Mouse ModelJournal of Medicinal Chemistry · 2026
6. Characterization of abatacept mediated immunogenicity using domain-specific and neutralizing antibody assays: a biosimilar perspectiveBioanalysis · 2026
7. Property-Biased Covalent DNA-Encoded Library Screening Enabled the Discovery of AM-8719, A Structurally Novel, CNS-Penetrant KRAS G12C InhibitorJournal of Medicinal Chemistry · 2026
8. Safety and Feasibility of Magnetic Separation‐Based Blood PurificationAdvanced NanoBiomed Research · 2026
9. Reinvestigation of the Isonicotinamide-Fluorobenzoic Acid Cocrystal: New Insights from Novel FormsCrystal Growth & Design · 2026
10. A Green, Facile, and Straightforward Synthesis of Pyrimidine‐2,4(1 H ,3 H )‐Diones From tert ‐Butyl (2‐Cyano Aryl/Heteroaryl) Carbamates: A Versatile Approach to Medicinally Relevant ScaffoldsChemistrySelect · 2026
11. The Development of UM-232, a Covalent STING AntagonistACS Medicinal Chemistry Letters · 2026
12. Drug Delivery Strategy Exploiting Amino Acid Prodrugs: Improving Oral Bioavailability and Overcoming Nonlinear Pharmacokinetic Challenges Following Dose Escalation of a CK2 Inhibitor with Poor SolubilityJournal of Medicinal Chemistry · 2026
13. Applications of Raman Spectroscopy in Early Phase Chemical DevelopmentOrganic Process Research & Development · 2026
14. Electrochemical synthesis of self immolative methylene alkoxy carbamate (MAC) to facilitate construction of antibody drug conjugate linkers with alcohol-containing payloadsSynthesis · 2026
15. Process Development for a TLR-7 Immunostimulatory Drug-Linker: Salt Screening and Precipitation for Drug-Linker IntermediatesOrganic Process Research & Development · 2026
16. Discovery of BMS-159, an Orally Active Imidazotriazine Pan-CK2 Inhibitor for the Treatment of CancerACS Medicinal Chemistry Letters · 2026
17. Synthesis of bioactive benzo[ d ] [1,3] dioxolyl–1,8-naphthyridine scaffolds and evaluation of their anticancer activitySynthetic Communications · 2026
18. Abstract 3909: SMARCA4 ablation mitigates distal-less homeobox 1 ( DLX1 )- driven oncogenicity in prostate cancer.Cancer Research · 2026
19. From Flat to 3D: Replacing Phenyl Rings with Saturated Bridged Bicyclic Mimetics to Mitigate Bioactivation and Optimize ADME Properties and Oral Bioavailability in Reverse Amide OrientationJournal of Medicinal Chemistry · 2026
20. Development of UM-200: A Novel Alkyne Amide-Based Inhibitor of the cGAS-STING PathwayJournal of Medicinal Chemistry · 2026