Evotec (United Kingdom)

Recent papers from Evotec (United Kingdom)

1. Assessing the state of the art in ADMET prediction: Lessons from the OpenADMET-ExpansionRx community blind challenge2026
2. Assessing the state of the art in ADMET prediction: Lessons from the OpenADMET-ExpansionRx community blind challenge2026
3. Assessing the state of the art in ADMET prediction: Lessons from the OpenADMET-ExpansionRx community blind challenge2026
4. To Flip or Notto Flip: Introducing the UniversalFlippability Index (UFI) for Epigenetic and Damaged NucleobasesChemical Research in Toxicology · 2026
5. Discovery of potent, selective and insurmountable MRGPRX2 antagonists for mast cell-driven disorders 2308475The Journal of Immunology · 2026
6. AI/ML-Accelerated Discovery of Oral α4β7 Integrin Inhibitors for Treating Inflammatory Bowel Disease 2327698The Journal of Immunology · 2026
7. Variability in manual editing of head and neck organs of interest auto-segmentations: a multi-user, longitudinal analysisRadiotherapy and Oncology · 2026
8. Quantifying manual editing time in autocontouring via audit log analysisPhysics and Imaging in Radiation Oncology · 2026
9. Quantifying the AI readiness gap: An international, multidisciplinary assessment of artificial intelligence literacy in the radiation oncology communityClinical and Translational Radiation Oncology · 2026
10. Thermodynamic Profiling and Fragment Screening of GPCRs Using Grating-Coupled InterferometrySLAS DISCOVERY · 2026
11. Discovery ofa Novel Lung-Restricted ALK5 Inhibitorfor the Treatment of Idiopathic Pulmonary FibrosisJournal of Medicinal Chemistry · 2026
12. Identification of the Piperidyl Urea Derivative BAY-439 as a Potent and Selective Inhibitor of Human Phospholipase A2 Group V (hPLA2-G5) for the Treatment of Inflammatory PainJournal of Medicinal Chemistry · 2026
13. A novel fusion tool to enable G protein-coupled receptor structure determinationActa Crystallographica Section D Structural Biology · 2026
14. The impact of DICOM import/export on radiotherapy structures in commercial systemsPhysics and Imaging in Radiation Oncology · 2026
15. Abstract 1750: Building an integrated platform for drug discovery in DNA damage responseCancer Research · 2026
16. Discovery of Potent, Selective, and Brain-Penetrant Small Molecule CD38 InhibitorsACS Medicinal Chemistry Letters · 2026
17. Potassium binding by carbonyl clusters, halophilic adaptation and catalysis of Haloferax mediterranei D-2-hydroxyacid dehydrogenaseCommunications Biology · 2025
18. The state of the art in dual-acting hybrid antibiotics to combat bacterial resistanceExpert Opinion on Drug Discovery · 2025
19. Design, Modular Synthesis and Screening of 58 Shape-Diverse 3-D Fragments2025
20. Isoindolinone-Based PET Tracers for Imaging Mutant Huntingtin AggregatesJournal of Medicinal Chemistry · 2025