Parkinson's Institute and Clinical Center

Recent papers from Parkinson's Institute and Clinical Center

1. Preservation of Extracellular and Tissue Dopamine During Tyrosine Hydroxylase Loss in Rat 6-OHDA Parkinson’s Model: Selective Compensation Restricted to Substantia NigraInternational Journal of Molecular Sciences · 2026
2. Long-term real-world effectiveness of carbidopa/levodopa enteral suspension after 36 months of treatment initiation in advanced Parkinson's disease in the US: final results from the PROviDE studyClinical Parkinsonism & Related Disorders · 2026
3. Parkinson’s Disease Drug Therapies in the Clinical Trial Pipeline: 2024 UpdateJournal of Parkinson s Disease · 2024
4. Delivering Multidisciplinary Rehabilitation Care in Parkinson’s Disease: An International Consensus StatementJournal of Parkinson s Disease · 2024
5. Investigating trial design variability in trials of disease-modifying therapies in Parkinson’s disease: a scoping review protocolBMJ Open · 2023
6. Predictive value of abbreviated olfactory tests in prodromal Parkinson diseasenpj Parkinson s Disease · 2023
7. Genome-wide association study identifies a new susceptibility locus in PLA2G4C for Multiple System Atrophy2023
8. Parkinson’s Disease Drug Therapies in the Clinical Trial Pipeline: 2023 UpdateJournal of Parkinson s Disease · 2023
9. Longitudinal clinical and biomarker characteristics of non-manifesting LRRK2 G2019S carriers in the PPMI cohortnpj Parkinson s Disease · 2022
10. Protein phosphatase 2A holoenzymes regulate leucine-rich repeat kinase 2 phosphorylation and accumulationNeurobiology of Disease · 2021
11. Differential Inhibition of LRRK2 in Parkinson's Disease Patient Blood by a G2019S Selective LRRK2 InhibitorMovement Disorders · 2021
12. Prospective Home-use Study on Non-invasive Neuromodulation Therapy for Essential TremorTremor and Other Hyperkinetic Movements · 2020
13. Parkinson’s Disease Drug Therapies in the Clinical Trial Pipeline: 2020Journal of Parkinson s Disease · 2020
14. LRRK2‐mediated Rab10 phosphorylation in immune cells from Parkinson's disease patientsMovement Disorders · 2018
15. Qualitative Evaluation of the Personal KinetiGraphTM Movement Recording System in a Parkinson’s ClinicJournal of Parkinson s Disease · 2018
16. A pathway for Parkinson’s Disease LRRK2 kinase to block primary cilia and Sonic hedgehog signaling in the braineLife · 2018
17. Genetic fine-mapping of the Iowan SNCA gene triplication in a patient with Parkinson’s diseasenpj Parkinson s Disease · 2018
18. Advancing Stem Cell Models of Alpha-Synuclein Gene Regulation in Neurodegenerative DiseaseFrontiers in Neuroscience · 2018
19. P62/SQSTM1 is a novel leucine-rich repeat kinase 2 (LRRK2) substrate that enhances neuronal toxicityBiochemical Journal · 2018
20. Optimizing Parkinson’s disease diagnosis: the role of a dual nuclear imaging algorithmnpj Parkinson s Disease · 2018