State Key Laboratory of Molecular Oncology

Recent papers from State Key Laboratory of Molecular Oncology

1. Multi-omics profiling suggests deep brain stimulation-associated expansion of CLIC3+ NK cells attenuates neuroinflammation in Parkinson's diseaseBiochemistry and Biophysics Reports · 2026
2. A plain language summary of results from the NeoADAURA study: treatment with osimertinib before surgery for patients with EGFR-mutated non-small cell lung cancer that can be surgically removedFuture Oncology · 2026
3. Discriminating malignancy of pulmonary nodules using a peripheral blood leukocyte DNA methylation-based SEMO network modelFrontiers in Oncology · 2026
4. Regulatory T cell instability facilitates blood–brain barrier disruption via the β-catenin-tight junctions axis, leading to perioperative neurocognitive disordersCell Death Discovery · 2026
5. Genome-wide CRISPR screening identifies UGCG-mediated metabolic reprogramming and autophagy as drivers of Niraparib resistance in ovarian cancerCell Communication and Signaling · 2026
6. Mortality and predictive models for 90-/180- day postoperative death for NSCLC patients aged ≥70 yearsJournal of Thoracic Disease · 2026
7. Exploratory Single-Cell Analysis of NK-Annotated Cells Across Marrow Compartments in Prostate Cancer Bone MetastasisCancer Investigation · 2026
8. Demoted CD4+ T-cell activity resulted from CTNNB1 mutations resists lenvatinib plus anti-PD1 in HCCCell Death and Disease · 2026
9. Multi-omics profiling uncovers diagnostic biomarker panel, progression-associated subtypes, and prognostic signature in pediatric mitochondrial diseaseNature Communications · 2026
10. Air pollution and early-onset lung cancer: from environmental carcinogenesis to early intervention strategies.2026
11. Development and validation of a machine learning model for the preoperative prediction of intractable hypoxemia in repeat lung surgerynpj Digital Medicine · 2026
12. Liver Metastases from Colorectal Cancer: From Pathogenesis to Current TreatmentMedComm · 2026
13. SETDB1 cooperates with the CRL4B complex to promote colorectal cancer tumorigenesis by disrupting circadian rhythmOncogene · 2026
14. PRMT1 and YBX1 cooperatively transcriptionally activate GPX4 to inhibit ferroptosis and promote breast cancer progressionCancer Letters · 2026
15. Multiomics profiling identifies molecular and cellular signatures of regular exercise in human peripheral bloodScience Advances · 2026
16. Spatial evolution of a cachexia-promoting microenvironment in pancreatic cancerCell · 2026
17. ICFinder: ion channel identification and ion permeation residue prediction using protein language modelsBMC Bioinformatics · 2026
18. CYPMol: A Single Model Framework Integrating Functional Residues with Protein Features and Molecule Embeddings to Predict CYP Substrates, Inhibitors, and Metabolism SitesJournal of Chemical Information and Modeling · 2026
19. First human decedent model of orthotopic multi-organ xenotransplantation: Whole liver and bilateral kidneys from a six-gene-edited pigMed · 2026
20. Definitive radiotherapy provides comparable survival with lower toxicity compared with concurrent chemoradiotherapy after long-course induction chemoimmunotherapy in unresectable non-small-cell lung cancerTherapeutic Advances in Medical Oncology · 2026