Hybrigenics (France)

Recent papers from Hybrigenics (France)

1. Characterisation and treatment of the cardiometabolic HFpEF phenogroupCardiovascular Research · 2026
2. A Cluster of Acidic Residues in the Cytoplasmic Domain of SARS-CoV-2 Spike is Required for Virion-Incorporation and Infectivity2025
3. Inhibition of tau neuronal internalization using anti-tau single domain antibodiesNature Communications · 2025
4. Role of TRIM24 in the regulation of proteasome-autophagy crosstalk in bortezomib-resistant mantle cell lymphomaCell Death Discovery · 2025
5. A selection and optimization strategy for single-domain antibodies targeting the PHF6 linear peptide within the tau intrinsically disordered proteinJournal of Biological Chemistry · 2024
6. Development of a V5-tag–directed nanobody and its implementation as an intracellular biosensor of GPCR signalingJournal of Biological Chemistry · 2023
7. MiniBAR/KIAA0355 is a dual Rac and Rab effector required for ciliogenesis2023
8. Strategy of selection and optimization of single domain antibodies targeting the PHF6 linear peptide within the Tau intrinsically disordered protein2023
9. WWOX binds MERIT40 and modulates its function in homologous recombination, implications in breast cancerCancer Gene Therapy · 2023
10. Secretion of VGF relies on the interplay between LRRK2 and post-Golgi v-SNAREsCell Reports · 2023
11. WWOX Binds MERIT40 and Modulates Its Function in Homologous Recombination, Implications in Breast Cancer2022
12. AUTS2 gene dosage affects synaptic AMPA receptors via a local dendritic spine AUTS2-TTC3-AKT-mTORC1 signaling dysfunction2022
13. Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s diseaseLife Science Alliance · 2022
14. Inhibition of Tau seeding by targeting Tau nucleation core within neurons with a single domain antibody fragmentMolecular Therapy · 2022
15. Regulation of Fibroblast Activation Protein-α Expression: Focus on Intracellular Protein InteractionsJournal of Medicinal Chemistry · 2021
16. Inhibition of Tau seeding by targeting Tau nucleation core within neurons with a single domain antibody fragment2021
17. Fr-PPIChem: An Academic Compound Library Dedicated to Protein–Protein InteractionsACS Chemical Biology · 2020
18. Detecting genetic variation and base modifications together in the same single molecules of DNA and RNA at base pair resolution using a magnetic tweezer platform2020
19. Chr21 protein-protein interactions: enrichment in products involved in intellectual disabilities, autism and Late Onset Alzheimer Disease2019
20. Nanobodies (VHHs) for targeting tau in Alzheimer's disease and tauopathiesIBRO Reports · 2019