Integral Molecular (United States)

Recent papers from Integral Molecular (United States)

1. Signatures of the neutralizing dengue virus-reactive memory B cell repertoire identified by multiplexed envelope dimer probes2026
2. Abstract 431: A new approach methodology (NAM) for specificity testing: ISTAND qualification of the membrane proteome array to evaluate off-target binding of MAb-based therapies.Cancer Research · 2026
3. Abstract 5535: GPRC5D multispecific antibodies: Engineering for affinity, cross-species reactivity, and bi/trispecific engagement in multiple myelomaCancer Research · 2026
4. Identification of the seven critical residues that control ZIKV-DENV cross-reactivity to engineer a non-cross-reactive ZIKV vaccineCell Reports · 2025
5. Development of Receptor-Integrated Magnetically Labeled Liposomes for Investigating SARS-CoV-2 Fusion InteractionsAnalytical Chemistry · 2025
6. Anti-Ebola virus mAb 3A6 protects highly viremic animals from fatal outcome via binding GP(1,2) in a position elevated from the virion membraneNature Communications · 2025
7. Specialized contact sites regulate the fusion of chlamydial inclusion membranesNature Communications · 2024
8. The emergence of cell-based protein arrays to test for polyspecific off-target binding of antibody therapeuticsmAbs · 2024
9. A VHH single-domain platform enabling discovery and development of monospecific antibodies and modular neutralizing bispecifics against SARS-CoV-2 variantsAntibody Therapeutics · 2024
10. Abstract 6743: Identifying new cellular adjuvants for cancer vaccines and immunotherapiesCancer Research · 2024
11. Abstract 2374: Bispecific and trispecific GPRC5D antibodies with potent cell-killing activity against multiple myelomaCancer Research · 2024
12. Abstract 718: CCR8 antibody drug conjugates: Targeting regulatory T cells for tumor sensitizationCancer Research · 2024
13. Abstract 5798: Preclinical safety assessment for specificity of biotherapeutics using the membrane proteome arrayCancer Research · 2024
14. Diverse array of neutralizing antibodies elicited upon Spike Ferritin Nanoparticle vaccination in rhesus macaquesNature Communications · 2024
15. Breaking barriers in antibody discovery: harnessing divergent species for accessing difficult and conserved drug targetsmAbs · 2023
16. Single B cell transcriptomics identifies multiple isotypes of broadly neutralizing antibodies against flavivirusesPLoS Pathogens · 2023
17. Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopesCell Reports · 2023
18. Targeting the Spike Receptor Binding Domain Class V Cryptic Epitope by an Antibody with Pan-Sarbecovirus ActivityJournal of Virology · 2023
19. Single B cell transcriptomics identifies multiple isotypes of broadly neutralizing antibodies against flaviviruses2023
20. Systematic analysis of human antibody response to ebolavirus glycoprotein shows high prevalence of neutralizing public clonotypesCell Reports · 2023