Horizon Discovery (United Kingdom)

Recent papers from Horizon Discovery (United Kingdom)

1. Abstract 456: Discovery of KAT6A degrader enabled by structural proteomics and AI.Cancer Research · 2026
2. Applications of artificial intelligence in drug discovery.2025
3. Blocking LIF and PD-L1 enhances the antitumor efficacy of SBRT in murine PDAC modelsJournal for ImmunoTherapy of Cancer · 2025
4. Morphological map of under- and over-expression of genes in human cells2024
5. Pancreatic CAF-Derived Autotaxin Drives Autocrine CTGF Expression to Modulate Protumorigenic SignalingMolecular Cancer Therapeutics · 2024
6. Recommendations from the AML molecular MRD expert advisory boardLeukemia · 2024
7. Abstract 7122: A novel USP1 inhibitor coupled with a novel proteomic response biomarker for precision oncology therapyCancer Research · 2024
8. SUMOylation of OsPSTOL1 is essential for regulating phosphate starvation responses in rice and ArabidopsisFrontiers in Plant Science · 2024
9. A review of behavioural rating scales for the assessment of Attention Deficit/Hyperactivity Disorder among adults in research2023
10. Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitisCell Genomics · 2023
11. SVEP1 influences monocyte to macrophage differentiation via integrin α4β1/α9β1 and Rho/Rac signallingBiochimica et Biophysica Acta (BBA) - Molecular Cell Research · 2023
12. JUMP Cell Painting dataset: morphological impact of 136,000 chemical and genetic perturbations2023
13. Immunohistochemical Expression of Tensin-4/CTEN in Squamous Cell Carcinoma in DogsVeterinary Sciences · 2023
14. The integrin ligand SVEP1 regulates GPCR‐mediated vasoconstriction via integrins α9β1 and α4β1British Journal of Pharmacology · 2022
15. Mechanistic insights into non-coding Y RNA processingRNA Biology · 2022
16. Genome Editing of Pluripotent Stem Cells for Adoptive and Regenerative Cell TherapiesGEN Biotechnology · 2022
17. Metabonomics study of the effects of single copy mutant KRAS in the presence or absence of WT allele using human HCT116 isogenic cell linesMetabolomics · 2021
18. Ubiquitination and degradation of SUMO1 by small-molecule degraders extends survival of mice with patient-derived tumorsScience Translational Medicine · 2021
19. A comparative analysis of recombinant Fab and full‐length antibody production in Chinese hamster ovary cellsBiotechnology and Bioengineering · 2021
20. Highly efficient multiplex genetic engineering of porcine primary fetal fibroblastsSurgery Open Science · 2020