HEC Pharm (China)

Recent papers from HEC Pharm (China)

1. Fast activity prediction of chemically modified siRNAs via structure-based energy calculations and inference-augmented tabular deep learningMolecular Therapy — Nucleic Acids · 2026
2. Preclinical characterization of HEC116094, an oral inhibitor of the influenza A virus polymerase PB2 subunitEmerging Microbes & Infections · 2026
3. Development of a Scalable Synthesis for the Spirocyclic Benzoxepane–Pyridine Core of FXR Agonist HEC96719Organic Process Research & Development · 2026
4. Potential of Chinese Mandarin Peel and Leaf (Agricultural Byproducts) as Candidate Ingredients for Functional Foods and FeedsFood Science & Nutrition · 2026
5. Abstract 2634: HEC-922:A CDH17-4-1BB bispecific antibody targeting CDH17 positive tumors shows potent anti-tumor activity.Cancer Research · 2026
6. Abstract 4570: HEC228032, an orally bioavailable molecular glue pan-RAS (ON) inhibitor with highly potent anti-tumor efficacyCancer Research · 2026
7. Abstract 416: HEC201625, a novel oral small molecule inhibitor of PD-L1, demonstrated potent anti-tumor activities both in vitro and in vivo .Cancer Research · 2026
8. Selective GLUT9 inhibitors for hyperuricemia via intestinal mechanismActa Pharmaceutica Sinica B · 2026
9. Systemic Immunity Triggered by Boron Neutron Capture Therapy via Manganese-Borate ComplexSHILAP Revista de lepidopterología · 2026
10. Enhanced Lincomycin Titer Through Knockout of GntR Family Regulator SLCG_2790 Combined With Fermentation Optimization in an Industrial Strain of Streptomyces lincolnensis L‐427Biotechnology Journal · 2026
11. An eco-friendly and rapid HPLC method for simultaneous determination of adenosine and ergothioneine in ten kinds of Cordyceps spp. samples with blue applicability grade index assessmentJournal of Food Composition and Analysis · 2026
12. Ultralow phosphorus achievement in vegetable oil degumming: Synergistic effects of citric acid chelation and trace NaOH flocculationLWT · 2025
13. Human iPSC-based breast cancer model identifies S100P-dependent cancer stemness induced by BRCA1 mutationScience Advances · 2025
14. Ag-Catalyzed Formal [2 + 4] Cycloaddition for the Diastereoselective Synthesis of Sterically Hindered 4-Aminochroman-2-ones from α-Diazopyrazoleamides and o-Hydroxy AldiminesThe Journal of Organic Chemistry · 2025
15. Extraction of lithium from cookeite-bearing claystone by chlorination roasting: From thermodynamic calculation to experimental practiceMinerals Engineering · 2025
16. Review of the Patent and Journal Literature: Synthesis and Final Forms of Antifungal Prodrug Isavuconazonium SulfateOrganic Process Research & Development · 2025
17. Early intervention of baicalin suppresses obesity-induced adipose tissue fibrotic remodeling through Interfering NF-κB/HIF-1ɑ/GRK2 Signaling PathwayPhytomedicine Plus · 2025
18. Electrocatalytic Hydrogen Evolution of Cobalt Triaryl Corrole Bearing Methylsulphonyl GroupChemistrySelect · 2025
19. Analytical Methods for the Determination of Apixaban in Pharmaceuticals and Biological Matrices: A Systematic ReviewCritical Reviews in Analytical Chemistry · 2025
20. Efficacy and safety of GLS4 with entecavir vs entecavir alone in chronic hepatitis B patients: A multicenter clinical trialJournal of Infection · 2025