Toa Pharmaceutical (Japan)

Recent papers from Toa Pharmaceutical (Japan)

1. A Two-Water-Assisted Deacylation Pathway in Class C β-Lactamase ACC-1 Revealed by High-Resolution Crystallography and QM/MM CalculationsACS Catalysis · 2026
2. Age of Zircons from Sedimentary Rocks of the Elgon Formation of the Ulban Terrane on the Coast of the Ulban BayRussian Journal of Pacific Geology · 2026
3. Pre-miR-21 Conformational Equilibrium Modulates the Efficacy of the Maturation Inhibitor L50ACS Chemical Biology · 2026
4. Abstract CT197: Phase I study of ERY974 in patients with glypican-3 (GPC-3)-positive advanced solid tumorsCancer Research · 2026
5. Abstract 5980: AUBE00: A novel cyclic peptide pan-KRAS inhibitor targeting KRAS-activated cancers including KRAS-mutant cancers and wild-type colorectal cancerCancer Research · 2026
6. Abstract 6457: Phase I study of STA551 (STA) a tumor-selective CD137 agonist, as monotherapy and in combination with atezolizumab (atezo) using CD8 PET imaging to assess pharmacodynamic effectsCancer Research · 2026
7. Guidelines for clinical electroencephalography: Russian professional community development and consensus buildingS S Korsakov Journal of Neurology and Psychiatry · 2026
8. Glabrol—an impurity in licorice extract—causes toxicity in muscle, bone, and immune tissues through activation of the AP-1 signaling pathwayFrontiers in Pharmacology · 2026
9. Feasibility of the photoacoustic detection of haemophilia-related microbleeds: a preclinical study using isolated pig limbsThrombosis Journal · 2026
10. Lactiplantibacillus plantarum TO-A Reduces Fat Accumulation in Caenorhabditis elegans via pept-1Microorganisms · 2026
11. Serum from patients with acetylcholine receptor antibody–positive myasthenia gravis triggers pathogenic changes in human myotube cellsJournal of Neuroimmunology · 2026
12. Flow cytometric distinction of mature spores of Bacillus subtilis 168 using Auramine OBioscience Biotechnology and Biochemistry · 2026
13. Indole-pyrimidine hybrids with anticancer therapeutic potentialFuture Medicinal Chemistry · 2026
14. Impact of the FDA roadmap and perspectives for regulatory use of new approach methodologies in Japanese pharmaceutical companiesNAM journal. · 2026
15. Infrared thermography for detecting compensatory load in people with haemophilia: a cross-sectional studyThrombosis Journal · 2025
16. Infrared thermography for detecting compensatory load in people with haemophilia: a cross-sectional studyThrombosis Journal · 2025
17. Major Progress in the Liquid-Phase Synthesis of N -Alkyl-Rich Cyclic Peptides: Kilogram-Scale GMP Production of the KRAS Inhibitor LUNA18Organic Process Research & Development · 2025
18. Probiotic strain Bacillus subtilis TO-A modulates the formation of neutrophil extracellular trapsGut Microbes Reports · 2025
19. Bacillus subtilis TO-A suppresses the age-related decline in locomotion in Caenorhabditis elegansCommunications Biology · 2025
20. Development of a Manufacturing Process for a Key (S)-5-(2,2-Dimethyltetrahydro-2H-pyran-4-yl)-1H-indole Intermediate for Orforglipron. Part I. Selection of an Evans Auxiliary-Assisted Asymmetric 1,4-Addition RouteOrganic Process Research & Development · 2025