GlycoMimetics (United States)

Recent papers from GlycoMimetics (United States)

1. Selectins in Biology and Human Disease: Opportunity in E-selectin AntagonismCureus · 2024
2. Combining 5‐azacitidine with the E‐selectin antagonist uproleselan is an effective strategy to augment responses in myelodysplasia and acute myeloid leukaemiaBritish Journal of Haematology · 2024
3. Targeting hematologic malignancies by inhibiting E-selectin: A sweet spot for AML therapy?Blood Reviews · 2024
4. FLT3 inhibitors upregulate CXCR4 and E-selectin ligands via ERK suppression in AML cells and CXCR4/E-selectin inhibition enhances anti-leukemia efficacy of FLT3-targeted therapy in AMLLeukemia · 2023
5. FLT3 inhibitors upregulate CXCR4 and E-selectin ligands through suppression of ERK in AML and combined inhibition of CXCR4/E-selectin enhances anti-leukemia efficacy of FLT3-targeted therapy2022
6. A randomized clinical trial of the efficacy and safety of rivipansel for sickle cell vaso-occlusive crisisBlood · 2022
7. Melatonin and andrographolide synergize to inhibit the colospheroid phenotype by targeting Wnt/beta‐catenin signalingJournal of Pineal Research · 2022
8. Phase 1/2 study of uproleselan added to chemotherapy in patients with relapsed or refractory acute myeloid leukemiaBlood · 2021
9. Targeting Neutrophil Adhesive Events to Address Vaso-Occlusive Crisis in Sickle Cell PatientsFrontiers in Immunology · 2021
10. Targeting E-Selectin with GMI-1271 Overcomes Microenvironment-Mediated Resistance to Venetoclax/HMA TherapyBlood · 2020
11. Protein kinase C‐δ interacts with and phosphorylates ARD1Journal of Cellular Physiology · 2020
12. Endothelial E-selectin inhibition improves acute myeloid leukaemia therapy by disrupting vascular niche-mediated chemoresistanceNature Communications · 2020
13. Use of GMI‐1271, an E‐selectin antagonist, in healthy subjects and in 2 patients with calf vein thrombosisResearch and Practice in Thrombosis and Haemostasis · 2020
14. Dual CXCR4 and E-Selectin Inhibitor, GMI-1359, Shows Anti-Bone Metastatic Effects and Synergizes with Docetaxel in Prostate Cancer Cell Intraosseous GrowthCells · 2019
15. Inhibition of E-Selectin (GMI-1271) or E-selectin together with CXCR4 (GMI-1359) re-sensitizes multiple myeloma to therapyBlood Cancer Journal · 2019
16. Guidelines Insights: Acute Lymphoblastic Leukemia, Version 1.2019Journal of the National Comprehensive Cancer Network · 2019
17. Clinical Trials and Applications of Galectin AntagonistsTrends in Glycoscience and Glycotechnology · 2018
18. P‐ and E‐selectin receptor antagonism prevents human leukocyte adhesion to activated porcine endothelial monolayers and attenuates porcine endothelial damageXenotransplantation · 2018
19. Upregulation of RASSF1A in Colon Cancer by Suppression of Angiogenesis Signaling and Akt ActivationCellular Physiology and Biochemistry · 2018
20. Selectin catch-bonds mechanotransduce integrin activation and neutrophil arrest on inflamed endothelium under shear flowBlood · 2017