Kyoto Pharmaceutical Industries (Japan)

Recent papers from Kyoto Pharmaceutical Industries (Japan)

1. A Novel Ultra‐Performance Liquid Chromatography‐Electrospray Ionisation‐Tandem Mass Spectrometry Method for Quantification of Imeglimin in Human Plasma: Application to a Bioequivalence StudyAnalytical Science Advances · 2026
2. Ethylenediaminetetraacetic acid conjugated with polyethylene glycol is a safe chelator for colonic epithelial denudation and intestinal epithelial replacement therapyScientific Reports · 2025
3. Conversion of pathogenic T cells into functionally stabilized T reg cells for antigen-specific immunosuppression in pemphigus vulgarisScience Translational Medicine · 2025
4. Synthesis and Structure–Activity Relationships of Novel Benzofuran Derivatives with Osteoblast Differentiation-Promoting ActivityChemical and Pharmaceutical Bulletin · 2025
5. A Novel Series of Coumarin Derivatives That Exert Osteoblastogenic Effects in Mesenchymal Stem Cells and Osteogenic Effects in Ovariectomized Female RatsChemical and Pharmaceutical Bulletin · 2024
6. Synthesis and Evaluation of a Novel Series of Diphenylamine and Diphenylether Derivatives with Osteoblastogenic and Osteogenic Effects via CDK8 InhibitionChemical and Pharmaceutical Bulletin · 2024
7. Osteoblastgenic and Osteogenic Effects of KY-273 with CDK8/19 Inhibitory Activity in Bone Marrow Mesenchymal Stem Cells and Female RatsBiological and Pharmaceutical Bulletin · 2024
8. Discovery of Novel Chromenopyridine Derivatives as Readthrough-Inducing DrugsChemical and Pharmaceutical Bulletin · 2023
9. Osteogenic Effects of KY-054, a Novel Coumarin Derivative on Femur Cortical Bone in Ovariectomized Female RatsBiological and Pharmaceutical Bulletin · 2023
10. Synthesis and Evaluation of Novel Triaryl Derivatives with Readthrough-Inducing ActivityChemical and Pharmaceutical Bulletin · 2023
11. Control of Accessible Surface Areas and Height Equivalent to a Theoretical Plate using Grafted Dextran during Anion-Exchange Chromatography of Therapeutic ProteinsJOURNAL OF CHEMICAL ENGINEERING OF JAPAN · 2022
12. The role of CDK8 in mesenchymal stem cells in controlling osteoclastogenesis and bone homeostasisStem Cell Reports · 2022
13. Synthesis and Evaluation of a Novel Series of 2,7-Substituted-6-tetrazolyl-1,2,3,4-tetrahydroisoquinoline Derivatives as Selective Peroxisome Proliferator-Activated Receptor γ Partial AgonistsChemical and Pharmaceutical Bulletin · 2021
14. Phenyl‐bonded monolithic silica capillary column liquid chromatographic separation and detection of fluorogenic derivatized intact proteinsBiomedical Chromatography · 2021
15. Metabolic alterations in plasma after laparoscopic sleeve gastrectomyJournal of Diabetes Investigation · 2020
16. Dietary short-chain fatty acid intake improves the hepatic metabolic condition via FFAR3Scientific Reports · 2019
17. (S)-1,2,3,4-Tetrahydroisoquinoline Derivatives Substituted with an Acidic Group at the 6-Position as a Selective Peroxisome Proliferator-Activated Receptor γ Partial AgonistChemical and Pharmaceutical Bulletin · 2019
18. A Novel Oral Anti-osteoporosis Drug with Osteogenesis-promoting Effects via Osteoblast DifferentiationYAKUGAKU ZASSHI · 2018
19. 2-Acyl-3-carboxyl-tetrahydroisoquinoline Derivatives: Mixed-Type PTP1B Inhibitors without PPARγ ActivationChemical and Pharmaceutical Bulletin · 2018
20. Serum Nardilysin, a Surrogate Marker for Epithelial–Mesenchymal Transition, Predicts Prognosis of Intrahepatic Cholangiocarcinoma after Surgical ResectionClinical Cancer Research · 2018