Toyama Prefectural Institute for Pharmaceutical Research

Recent papers from Toyama Prefectural Institute for Pharmaceutical Research

1. Immunomodulatory Effect of Shakuyaku (Paeoniae Radix) Extract and Its Use for Preventing Inflammatory Bowel DiseaseTraditional & Kampo Medicine · 2026
2. PDGFRα governs multiple cellular signals and plays a protective role in tumor progressionNeoplasia · 2025
3. Cholic Acid–Induced Akkermansia Expansion and FGF ‐15 Upregulation Improve Diabetes While Exacerbating Steatohepatitis in TSOD MiceGenes to Cells · 2025
4. Improvement of culture and acclimation conditions in a bio-nursery system for Paeonia lactifloraPlant Biotechnology · 2025
5. IL-5-producing Group 2 innate lymphoid cells promote T cell-independent IgA production in cooperation with eosinophilsInternational Immunology · 2024
6. Preparation of stable and monodisperse paclitaxel-loaded bovine serum albumin nanoparticles via intermolecular disulfide crosslinkingBiochemistry and Biophysics Reports · 2024
7. Isoliquiritigenin inhibits NLRP3 inflammasome activation with CAPS mutations by suppressing caspase‐1 activation and mutated NLRP3 aggregationGenes to Cells · 2024
8. Analysis of Factors Related to Variation in Dissolution Profiles Estimated from Continuously Conducted Dissolution Tests of Generic ProductsChemical and Pharmaceutical Bulletin · 2023
9. Lung group 2 innate lymphoid cells differentially depend on local IL-7 for their distribution, activation, and maintenance in innate and adaptive immunity-mediated airway inflammationInternational Immunology · 2023
10. Development of a recombinant hepatitis B immunoglobulin derived from B cells collected from healthy individuals administered with hepatitis B virus vaccines: A feasibility studyTransfusion · 2023
11. Impact of Vancomycin Treatment and Gut Microbiota on Bile Acid Metabolism and the Development of Non-Alcoholic Steatohepatitis in MiceInternational Journal of Molecular Sciences · 2023
12. Estimation of pollen dispersal distance in Job’s tears (Coix lacryma-jobi L.) by using red leaf sheath as a morphological markerIkushugaku zasshi · 2023
13. Human antibody recognition and neutralization mode on the NTD and RBD domains of SARS-CoV-2 spike proteinScientific Reports · 2022
14. Roles of Macrophages in Advanced Liver Fibrosis, Identified Using a Newly Established Mouse Model of Diet-Induced Non-Alcoholic SteatohepatitisInternational Journal of Molecular Sciences · 2022
15. A Liquid Chromatography-Mass Spectrometry Method to Study the Interaction between Membrane Proteins and Low-Molecular-Weight Compound MixturesMolecules · 2022
16. Isoliquiritigenin Attenuates Adipose Tissue Inflammation and Metabolic Syndrome by Modifying Gut Bacteria Composition in MiceMolecular Nutrition & Food Research · 2022
17. Betulin Attenuates TGF-β1- and PGE2-Mediated Inhibition of NK Cell Activity to Suppress Tumor Progression and Metastasis in MiceBiological and Pharmaceutical Bulletin · 2022
18. Optimization of anti-ADAMTS13 antibodies for the treatment of ADAMTS13-related bleeding disorder in patients receiving circulatory assist device supportScientific Reports · 2021
19. Anticancer Effect of Epitheaflagallin 3-O-Gallate, a Very Minor Constituent of Black Tea ExtractACS Food Science & Technology · 2021
20. Bone marrow transplantation into Abcd1‐deficient mice: Distribution of donor derived‐cells and biological characterization of the brain of the recipient miceJournal of Inherited Metabolic Disease · 2020