Mithra Pharmaceuticals (Belgium)

Recent papers from Mithra Pharmaceuticals (Belgium)

1. Procoagulant off-target effect of the direct oral anticoagulant reversal agent andexanet alfaSHILAP Revista de lepidopterología · 2025
2. Role of Membrane Estrogen Receptor Alpha on the Positive Feedback of Estrogens on Kisspeptin and GnRH NeuronseNeuro · 2024
3. Efficacy and safety of the combination of estetrol 15 mg/drospirenone 3 mg in a cyclic regimen for the treatment of endometriosis-associated pain and objective gynecological findings: a multicenter, placebo-controlled, double-blind, randomized studyFertility and Sterility · 2024
4. Effects of E4/DRSP on self-reported physical and emotional premenstrual and menstrual symptoms: data from the phase 3 clinical trial in Europe and RussiaThe European Journal of Contraception & Reproductive Health Care · 2024
5. P03 Anti-ageing effects of oestetrol on the skin: protection from cellular senescence and restoration of dermal architectureBritish Journal of Dermatology · 2024
6. Estetrol/GPER/SERPINB2 transduction signaling inhibits the motility of triple-negative breast cancer cellsJournal of Translational Medicine · 2024
7. Estetrol/drospirenone versus 17α-ethinylestradiol/drospirenone: An extended one generation test to evaluate the endocrine disruption potential on zebrafish (Danio rerio)Environment International · 2024
8. Low thrombin generation in postmenopausal women using estetrolClimacteric · 2024
9. Impact of Estetrol Combined with Drospirenone on Blood Coagulation and Fibrinolysis in Patients with Endometriosis: A Multicenter, Randomized, Open-Label, Active-Controlled, Parallel-Group StudySHILAP Revista de lepidopterología · 2024
10. Role of membrane estrogen receptor alpha ( ERα ) in the rapid regulation of male sexual behaviorJournal of Neuroendocrinology · 2023
11. The benefits of estetrol addition to drospirenone for contraceptionAJOG Global Reports · 2023
12. Estetrol Is Safe and Well Tolerated during Treatment of Hospitalized Men and Women with Moderate COVID-19 in a Randomized, Double-Blind StudyJournal of Clinical Medicine · 2023
13. Estetrol: From Preclinical to Clinical Pharmacology and Advances in the Understanding of the Molecular Mechanism of ActionDrugs in R&D · 2023
14. Hormonal therapies and venous thrombosis: considerations for prevention and management—a reappraisalResearch and Practice in Thrombosis and Haemostasis · 2023
15. Combined Oral Contraceptive Adherence and Pregnancy RatesObstetrics and Gynecology · 2023
16. Role of membrane estrogen receptor alpha on the positive feedback of estrogens on LH secretion2023
17. A multicenter, randomized, placebo-controlled study to select the minimum effective dose of estetrol in postmenopausal participants (E4Relief): part 2—vaginal cytology, genitourinary syndrome of menopause, and health-related quality of lifeMenopause The Journal of The North American Menopause Society · 2023
18. Metal-free synthesis of an estetrol key intermediate under intensified continuous flow conditionsReaction Chemistry & Engineering · 2023
19. Response to paper by Binkowska et al. Risk of venous thromboembolism during the use of oral estrogen-progestogen hormone therapies in light of most recent research findings. Commentary: Oestradiol is not the holy grail in the quest for the ideal oestrogen therapyMenopause Review/Przegląd Menopauzalny · 2023
20. Impact of estetrol (E4) on hemostasis, metabolism and bone turnover in postmenopausal womenClimacteric · 2022