ProLynx (United States)

Recent papers from ProLynx (United States)

1. PEG-RLI: A Long-Acting IL-15 Agonist That Produces Massive Levels of CD8+ and CD44hiCD8+ Cells for Cancer ImmunotherapyPharmaceutics · 2026
2. Pathophysiological and therapeutic implications of C-type natriuretic peptide/cyclic GMP signaling in pulmonary fibrosisJCI Insight · 2026
3. Antitumor activity of rucaparib plus PLX038A in serous endometrial carcinomaJournal of Experimental & Clinical Cancer Research · 2025
4. Long-Acting, Longer-Acting, and Ultralong-Acting Antiobesity PeptidesJournal of Medicinal Chemistry · 2025
5. The limitation of lipidation: Conversion of semaglutide from once-weekly to once-monthly dosingProceedings of the National Academy of Sciences · 2024
6. Leveraging long-acting IL-15 agonists for intratumoral delivery and enhanced antimetastatic activityFrontiers in Immunology · 2024
7. PET Imaging Using 89Zr Labeled StarPEG Nanocarriers Reveals Heterogeneous Enhanced Permeability and Retention (EPR) in Prostate CancerMolecular Cancer Therapeutics · 2024
8. The limitation of lipidation: conversion of semaglutide from once-weekly to once-monthly dosing2024
9. PLX038A, a long-acting SN-38, penetrates the blood-tumor-brain-barrier, accumulates and releases SN-38 in brain tumors to increase survival of tumor bearing miceScientific Reports · 2024
10. A platform technology for ultra-long acting intratumoral therapyScientific Reports · 2024
11. Phase II clinical trial of PLX038 in patients with platinum resistant ovarian, primary peritoneal and fallopian tube cancer.Journal of Clinical Oncology · 2024
12. Synergistic Antitumor Activity of Talazoparib and Temozolomide in Malignant Rhabdoid TumorsCancers · 2024
13. Prostate‐Specific Membrane Antigen Targeted StarPEG Nanocarrier for Imaging and Therapy of Prostate CancerAdvanced Healthcare Materials · 2024
14. Development of a long acting c-natriuretic peptide suitable for QMo dosing2024
15. Long-Acting Poly(ADP-ribose) Polymerase Inhibitor Prodrug for HumansBioconjugate Chemistry · 2024
16. Abstract LB439: Intra-tumoral administration of releasable hydrogel microsphere drug conjugates for long acting therapeuticsCancer Research · 2024
17. Releasable hydrogel microsphere-drug conjugates as generic prodrugs for long-acting intra-tumoral therapy2024
18. Could a Long-Acting Prodrug of SN-38 be Efficacious in Sacituzumab Govitecan-Resistant Tumors?BioDrugs · 2024
19. Prostate-Specific Membrane Antigen Targeted Deep Tumor Penetration of Polymer NanocarriersACS Applied Materials & Interfaces · 2022
20. A long-acting C-natriuretic peptide for achondroplasiaProceedings of the National Academy of Sciences · 2022