Cyrus Biotechnology

Recent papers from Cyrus Biotechnology

1. Modulation of the pharmacokinetics of soluble ACE2 decoy receptors through glycosylationMolecular Therapy — Methods & Clinical Development · 2024
2. Deep mutational scanning reveals sequence to function constraints for SWEET family transporters2024
3. Pos1410 Long-Acting Derivatives of a Bacterial Igg Protease With Reduced Immunogenicity for the Rapid Degradation of Igg AutoantibodiesAnnals of the Rheumatic Diseases · 2024
4. Sequence basis for selectivity of ephrin-B2 ligand for Eph receptors and pathogenic henipavirus G glycoproteinsJournal of Virology · 2023
5. Multiple mechanisms of self-association of chemokine receptors CXCR4 and CCR5 demonstrated by deep mutagenesisJournal of Biological Chemistry · 2023
6. A computationally designed ACE2 decoy has broad efficacy against SARS-CoV-2 omicron variants and related viruses in vitro and in vivoThe Medicine Forum · 2023
7. The Sequence Basis for Selectivity of Ephrin-B2 Ligand for Eph Receptors and Pathogenic Henipavirus G Glycoproteins2023
8. Multiple mechanisms of self-association of chemokine receptors CXCR4 and CCR5 demonstrated by deep mutagenesis2023
9. Machine Learning Guided Design of High-Affinity ACE2 Decoys for SARS-CoV-2 NeutralizationThe Journal of Physical Chemistry B · 2023
10. An ACE2 decoy can be administered by inhalation and potently targets omicron variants of SARS‐CoV‐2EMBO Molecular Medicine · 2022
11. Computational Site Saturation Mutagenesis of Canonical and Non-Canonical Amino Acids to Probe Protein-Peptide InteractionsFrontiers in Molecular Biosciences · 2022
12. An engineered ACE2 decoy receptor can be administered by inhalation and potently targets the BA.1 and BA.2 omicron variants of SARS-CoV-22022
13. Engineered ACE2 decoy mitigates lung injury and death induced by SARS-CoV-2 variantsNature Chemical Biology · 2022
14. Engineered High-Affinity ACE2 Peptide Mitigates ARDS and Death Induced by Multiple SARS-CoV-2 Variants2021
15. Ensuring scientific reproducibility in bio-macromolecular modeling via extensive, automated benchmarksNature Communications · 2021
16. Linseed and Its Basic CompositionInternational Journal of Advances in Agricultural Science and Technology · 2021
17. Ensuring scientific reproducibility in bio-macromolecular modeling via extensive, automated benchmarks2021
18. Prediction of Protein Mutational Free Energy: Benchmark and Sampling Improvements Increase Classification AccuracyFrontiers in Bioengineering and Biotechnology · 2020
19. Better together: Elements of successful scientific software development in a distributed collaborative communityPLoS Computational Biology · 2020
20. Macromolecular Modeling and Design in Rosetta: New Methods and Frameworks2019