Prana Biotechnology (Australia)

Recent papers from Prana Biotechnology (Australia)

1. Targeting metals rescues the phenotype in an animal model of tauopathyMetallomics · 2018
2. A randomized, exploratory molecular imaging study targeting amyloid β with a novel 8‐OH quinoline in Alzheimer's disease: The PBT2‐204 IMAGINE studyAlzheimer s & Dementia Translational Research & Clinical Interventions · 2017
3. The novel compound PBT434 prevents iron mediated neurodegeneration and alpha-synuclein toxicity in multiple models of Parkinson’s diseaseActa Neuropathologica Communications · 2017
4. Cardiac Light Chain Amyloidosis: The Role of Metal Ions in Oxidative Stress and Mitochondrial DamageAntioxidants and Redox Signaling · 2017
5. PBT2 Reduces Toxicity in a C. elegans Model of polyQ Aggregation and Extends Lifespan, Reduces Striatal Atrophy and Improves Motor Performance in the R6/2 Mouse Model of Huntington's DiseaseJournal of Huntington s Disease · 2012
6. The Alzheimer’s therapeutic PBT2 promotes amyloid‐β degradation and GSK3 phosphorylation via a metal chaperone activityJournal of Neurochemistry · 2011
7. PBT2 Rapidly Improves Cognition in Alzheimer's Disease: Additional Phase II AnalysesJournal of Alzheimer s Disease · 2010
8. Crystal Structures of Neuraminidase-Antibody ComplexesCold Spring Harbor Symposia on Quantitative Biology · 1989