Synimmune (Germany)

Recent papers from Synimmune (Germany)

1. IDH1-mutant vaccine in newly diagnosed astrocytoma: final analysis of the multicenter, single-arm, open-label, first-in-human phase 1 NOA16 trialNature Cancer · 2026
2. Development of CAR NK Cell Lines Selectively Targeting Cancer Cells Expressing Membrane Hsp70MedComm · 2026
3. Phase I study evaluating the Fc-optimized FLT3 antibody FLYSYN in AML patients with measurable residual diseaseJournal of Hematology & Oncology · 2023
4. Blocking FcRn in humans reduces circulating IgG levels and inhibits IgG immune complex–mediated immune responsesScience Advances · 2019
5. Reduction of Minimal Residual Disease in Pediatric B-lineage Acute Lymphoblastic Leukemia by an Fc-optimized CD19 AntibodyMolecular Therapy · 2016
6. Induction of NK and T Cell Immune Responses Against Leukemia Cells By Bispecific NKG2D-CD16 and -CD3 Fusion ProteinsBlood · 2015
7. Induction of NK Cell Reactivity Against Myeloid Leukemia By a Novel Fc-Optimized CD133 AntibodyBlood · 2015
8. A Recombinant Bispecific CD20×CD95 Antibody With Superior Activity Against Normal and Malignant B-cellsMolecular Therapy · 2015
9. Characterization of a Bispecific FLT3 X CD3 Antibody in an Improved, Recombinant Format for the Treatment of LeukemiaMolecular Therapy · 2015
10. Development and Preclinical Characterization of an Fc-Optimized CD133 Antibody for Induction of NK Cell Reactivity Against Myeloid LeukemiaBlood · 2014
11. γδ T Cell-Mediated Antibody-Dependent Cellular Cytotoxicity with CD19 Antibodies Assessed by an Impedance-Based Label-Free Real-Time Cytotoxicity AssayFrontiers in Immunology · 2014