Supplementary Figure S2 from T-cell Dependency of Tumor Regressions and Complete Responses with RAS(ON) Multi-selective Inhibition in Preclinical Models of Pancreatic Ductal Adenocarcinoma
Key Points
Multi-selective inhibition of RAS(ON) significantly lowers pERK expression in PDAC tumors.
The findings highlight the role of T-cell activity in tumor regression and responses observed.
The research utilizes preclinical models to explore the effects of targeted inhibition on pancreatic tumors.
This work advances understanding of treatment strategies for pancreatic ductal adenocarcinoma, emphasizing immune system involvement.
Supplementary Figure S2 from T-cell Dependency of Tumor Regressions and Complete Responses with RAS(ON) Multi-selective Inhibition in Preclinical Models of Pancreatic Ductal Adenocarcinoma | Synapse