Supplementary Figure 16 from Defining the Ovarian Cancer Precancerous Landscape through Modeling Fallopian Tube Epithelium Reprogramming Driven by Extracellular Vesicles
Key Points
MAIN FINDING: Upregulated transcripts from OVCAR3 extracellular vesicles are linked to cancer progression.
KEY EVIDENCE: Transcripts associated with precursor lesions show upregulation in invasive cancer stages.
APPROACH: The study uses modeling to explore fallopian tube epithelium reprogramming driven by extracellular vesicles.
SIGNIFICANCE: Understanding these mechanisms may help in defining ovarian cancer's precancerous landscape.
Abstract
Transcripts upregulated by OVCAR3 EVs are also upregulated in progression from precursor lesion to invasive cancer.
Supplementary Figure 16 from Defining the Ovarian Cancer Precancerous Landscape through Modeling Fallopian Tube Epithelium Reprogramming Driven by Extracellular Vesicles | Synapse