Systematic review and meta-analysis: plant based therapy for functional dyspepsia

Introduction: Functional dyspepsia (FD) is characterized by symptoms such as bloating, early satiety, epigastric pain, and burning, with a global prevalence ranging from 11% to 29%. The causes are multifactorial, including motility disturbances, visceral hypersensitivity, immune activation and psychosocial factors. FD is classified according to the Rome IV criteria into postprandial distress syndrome and epigastric pain syndrome. It is associated with reduced quality of life and comorbid psychiatric disorders, highlighting the need for effective treatment. Many FD patients prefer herbal preparations to pharmaceutical medication. However, the efficacy of this form of therapy is uncertain.