Herbal Remedies as Adjunct Therapies for Rheumatoid Arthritis: Focus on Ginger: A Review

Rheumatoid Arthritis (RA) is a chronic autoimmune disorder characterized by persistent joint inflammation, pain, and progressive disability. While conventional pharmacological treatments remain the cornerstone of RA management, growing interest in alternative and complementary therapies has drawn attention to the medicinal potential of natural compounds such as ginger (Zingiber officinale). This review investigates the therapeutic role of ginger in alleviating RA-related symptoms, with a particular focus on its anti-inflammatory and immunomodulatory mechanisms. Bioactive constituents such as gingerols and shogaols have demonstrated the ability to inhibit pro-inflammatory cytokines and oxidative stress pathways implicated in RA pathogenesis. Clinical and preclinical studies provide preliminary evidence supporting ginger's efficacy and safety. This paper highlights current findings and outlines future directions for integrating ginger as a complementary therapeutic option in RA management.