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September 10, 2025
Open Access
Retracted Apigenin induces apoptosis and counteracts cisplatin‑induced chemoresistance via Mcl‑1 in ovarian cancer cells
YQ
Yuyan Qi
Qingdao University
ZD
Zhaoxia Ding
Qingdao University
YY
Yushuang Yao
Qingdao University
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Key Points
Apigenin effectively induces apoptosis in ovarian cancer cells, combating cisplatin-induced chemoresistance.
The mechanism involves modulation of Mcl-1, suggesting a new therapeutic target for overcoming treatment resistance.
Cisplatin, a common chemotherapy drug, faces challenges due to resistance, making apigenin's role crucial in treatment strategies.
These findings support future investigations on apigenin's potential in clinical applications for ovarian cancer.
Abstract
This retracts the article DOI: 10.3892/etm.2020.8880..
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Retracted Apigenin induces apoptosis and counteracts cisplatin‑induced chemoresistance via Mcl‑1 in ovarian cancer cells | Synapse
Cite This Study
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Qi et al. (Mon,) studied this question.
synapsesocial.com/papers/68c1c23d54b1d3bfb60efe96
https://doi.org/https://doi.org/10.3892/etm.2025.12941