What type of study is this?

This is a Experimental Study study.

September 17, 2025

Wireless EEG System for Concurrent TMS-EEG-fMRI

Key Points

The wireless EEG system shows stable operation within the MRI bore, minimizing disruptions from imaging sequences.
Results demonstrate effective communication with the SCμM-3C and Texas Instruments ADS1299 during functional MRI exposure.
The new prototype aims to advance concurrent TMS-EEG-fMRI studies with fewer safety concerns and reduced interference from electrical connections.
Ongoing developments focus on miniaturizing the system for better integration with custom EEG front-ends in neuroimaging setups.

Abstract

Motivation: We present a novel approach to challenges posed by concurrent TMS-EEG-fMRI systems, using a wireless EEG system based on the Single Chip Micro Mote (SCμM). Goal(s): This approach could enable safer, more effective multimodal brain imaging and stimulation studies by eliminating long wires and large loop areas in the MRI environment. Approach: We demonstrate a prototype using SCμM-3C with Texas Instruments ADS1299 on an MRI-safe PCB. Results: Our results show stable operation and communication from within the bore with minimal disruption from structural and functional MRI sequences. Ongoing work aims to miniaturize the system by integrating a custom EEG front-end onto SCμM. Impact: This wireless EEG system aims to advance multimodal neuroimaging by enabling concurrent TMS-EEG-fMRI studies with reduced interference and improved safety. The system may improve the many relevant diagnostic and therapeutic applications in neuroscience. The presented prototype is made open-source.

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