What type of study is this?

October 2, 2025

Stargardt Disease Diagnosed With Spectral-Domain Oct and Perimetry in the Absence of Fundus Autofluorescence and Fluorescein Angiography: A Case Report

Key Points

A combination of clinical findings and imaging techniques led to a diagnosis of stargardt disease with no autofluorescence imaging available.
Optical coherence tomography showed disruption in the ellipsoid zone and thinning of the outer nuclear layer, critical for diagnosis.
Automated perimetry revealed dense central scotomas, highlighting the impact of stargardt disease on vision.
This case contributes to understanding diagnostic approaches when conventional imaging methods are unavailable.

Abstract

Purpose: To report a case of Stargardt disease diagnosed on the basis of clinical phenotype, spectral-domain optical coherence tomography (SD-OCT), and automated perimetry, in the absence of fundus fluorescein angiography (FFA) and fundus autofluorescence (FAF). Detailed ophthalmic evaluation, multimodal imaging, and functional Methods: tests were performed. A 36-year-old male presented with progressive bilateral central vision loss. Fundus Results: examination revealed characteristic yellow–white flecks and macular atrophy. OCT demonstrated ellipsoid zone disruption, outer nuclear layer thinning, and hyperreflective deposits at the level of the retinal pigment epithelium. Automated perimetry showed dense central scotomas with preserved peripheral fields. In settings wher Conclusion: e FAF and FFA are not available, a combination of clinical findings, OCT, and perimetry can provide sufficient evidence to establish a diagnosis of Stargardt disease.

AIに質問

Bookmark

Cite This Study

Debsikdar et al. (Mon,) studied this question.

synapsesocial.com/papers/68de5da783cbc991d0a20e85 https://doi.org/https://doi.org/10.36106/paripex/5404934

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

AIに質問

Bookmark