Application of whole-tumor histogram analysis of restriction spectrum imaging in the diagnosis of benign and malignant liver lesions

Restricted spectrum imaging (RSI) is an advanced technique, which can detect the signal fractions of restricted, hindered and free diffusion of water molecules in the water compartments inside and outside the cell. However, the application of RSI in the assessment of liver disease is rare. Therefore, this study was to evaluate the diagnostic performance of RSI and DWI models in distinguishing benign and malignant liver lesions. Our results showed that the RSI model has better discriminative performance, and the combination of RSI parameters can further improve diagnostic performance. RSI provides a new perspective for exploring the information of tissue microenvironment, and its clinical application has broad prospects.