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This study investigated the feasibility of spatially explicit analysis based on IVIM MRI to identify hypoxia-related habitats with higher-grade glioma, and to predict progress-free survival in patients. The results showed that spatial explicit analysis on IVIM MRI could be an appropriate method for distinguishing different hypoxic subregions in glioma. In addition, the volume percentage of less hypoxic habitats can effectively predict progress-free survival in higher-grade glioma.
Wang et al. (Wed,) studied this question.
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