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High-b-value DWI has been widely applied in clinical practices, but it is challenging to acquire several high b-value images for long acquisition time and more eddy distortion as b-value increases, leading to patient discomfort, increased motion artifacts and decreased SNR. High-b-value SyDWIs showed better SNR and less image distortion than scanned high-b-value DWIs. Our study demonstrate the feasibility of 5b-value synthetic high-b-value reduced full-of-view diffusion weighted imaging with the pros of short scan time, better lesion clarity and higher image quality in comparison of 13b-protocol rFOV-syDWIs and 5b-protocol synthetic ADCmean and ADCminimum offered reliably diagnostic value compared to 13b-protocol ones.
Tang et al. (Wed,) studied this question.