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Kidney Transplanted is the therapyfor patients with end-stage renal disease. Arterial spin labeling (ASL) uses magnetic labeling of water from inflowing blood as an endogenous tracer to acquire maps of absolute regional perfusion. The purpose of this study was to evaluate the blood flow of transplanted kidney allograft using a 1.5T MRI with ASL technique and determine whether renal allograft cortical perfusion by ASL could be a non-invasive biomarker for identifying kidney allograft function. Our data showed DWI and 3D-pCASL could be quantitative non-invasive tools for the clinical translation of identifying kidney allografts with subclinical pathology in further study.
Zhang et al. (Wed,) studied this question.