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Hepatic stiffness measured by MR elastography (MRE) is a biomarker for fibrosis. Standard liver MRE requires breath-holding (BH) to avoid motion artifacts, but BH is challenging for children. Radial free-breathing (FB) MRE can overcome this challenge but requires longer scan times. Radial FB-MRE using rapid wave encoding decreases the scan time and self-navigation supports motion compensation. With the help of fractional encoding to reduce echo times, image quality can be further improved. This work demonstrated that self-navigated rapid and rapid fractional FB-MRE methods measure hepatic stiffness with close agreement and similar repeatability compared to corresponding BH-MRE in children at 3T.
Kafalı et al. (Wed,) studied this question.
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