Repeatability of R1, R2* and fat fraction in Human Lumbar Vertebrae using a simultaneous multi-relaxation-time Imaging (TXI) method

The quantitative MRI mapping techniques showed great potential in evaluating intervertebral disc degeneration (IVD) and diagnosing lower back pain. The repeatability of the quantitative methods is very important for clinical evaluation. A simultaneous multi-relaxation-time mapping (TXI) method was evaluated here, which can quantify the bone marrow fat fraction (BMFF), R2* and R1 value by a single scan and fast speed. The quantitative parameters of TXI showed high repeatability with high consistency and low CoVs, and could be applied in future clinical applications of IVD degeneration disease.