Single-shot, Multi-TI Late Gadolinium Enhancement MRI using GRASP-Pro Reconstruction with View-Sharing and KWIC Filtering

Late gadolinium enhancement (LGE) is the clinical standard for assessment of myocardial scarring. Current limitations of standard LGE are lengthy scan time, sensitivity to arrhythmia and/or dyspnea, and reliance of optimal inversion time (TI), which may be difficult to identify for patients with subendocardial scarring. We propose a free-breathing, single-short, multi-TI LGE approach to address the aforementioned challenges. Our results show that GRASP-Pro reconstruction with view-sharing (VS) and k-space weighted image contrast (KWIC) filtering produces multi-TI LGE images (i.e., no need for TI scout) with relatively high spatial resolution.