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Gels appear to be a more favorable formulation to use in both medicinal and cosmetic applications when compared to other semisolid formulations. Emulgel is the term for the combination of gel and emulsion applications. pharmaceutical arrangements. Emulgel is the term for the combination of gel and emulsion applications. The most promising medication delivery method for hydrophobic medicines is emulgel. Emulgel is an intriguing topical drug delivery method that possesses both a gel and an emulsion dual release control system. Emulgel has a number of benefits, including being transparent, emollient, readily spreadable, and easily removed. The main drawback of this approach is that the stratum corneum, or outermost layer of skin, acts as a barrier to protect the underlying tissues from the external environment, making it difficult for the medications to pass through the skin. A transdermally delivered medication can only be effective if it can pass through the transdermal barrier and enter the systemic circulation. Penetration enhancers are substances that make the skin more permeable, which in turn keeps the drug level in the blood stable. Chemical, natural, and physical penetration enhancers are the three different types available. This review discusses natural permeation enhancers that can be used to improve medication transdermal penetration.
- et al. (Tue,) studied this question.