One of the leading problems in modern allergology is drug hypersensitivity. There is an increase in allergic reactions to medications that are commonly used in routine practice. The article presents a clinical case of a patient who developed anaphylaxis following the simultaneous administration of local anesthetics and chlorhexidine. Data on drug allergy (DA) to antiseptic agents are discussed. As a part of diagnostic workup in vitro and in vivotesting with suspected drugs was conducted, resulting in confirmation of DA to chlorhexidine, which led to the prohibition of its use and ruled out allergy to local anesthetics.
Pinchuk et al. (Mon,) studied this question.