October 19, 2025Open Access

Effectiveness of the autumnal COVID-19 vaccine dose during the winter and summer waves of the 2023/24 season in Spain

Key Points

Vaccine effectiveness was assessed for the COVID-19 XBB.1.5 vaccine, showing its impact during two epidemic waves in Spain.
Effectiveness against hospitalization was significant, with specific focus on individuals aged 60 and older.
Analysis covered both winter and summer waves, indicating seasonal variance in vaccine performance.
Findings emphasize the importance of vaccine uptake among older demographics in managing COVID-19 outcomes.

Abstract

Background We estimated vaccine effectiveness (VE) of the COVID-19 monovalent XBB.1.5 vaccine recommended in Spain in October 2023 for ≥60-year-olds against medically-attended COVID-19 and COVID-19 hospitalization, during winter and summer epidemic waves.

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Cite This Study

Rojas‐Benedicto et al. (Fri,) studied this question.

synapsesocial.com/papers/68f43f03854d1061a58ac417 https://doi.org/https://doi.org/10.1080/14760584.2025.2576243

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