Objectives: Endoscopy is the gold standard for determining the diagnostic accuracy of the platelet count/spleen diameter ratio in predicting esophageal varices in individuals with liver cirrhosis. Study Type: Cross-sectional (validation) study. Settings: Department of Medicine, Allied Hospital, Faisalabad. Study Period: 24th June 2024 to 23rd December 2024. Methodology: The study comprised 199 patients aged 18 to 80 years presenting with liver cirrhosis having suspected esophageal varices. Patients with a h/o previously treated esophageal varices, hepatocellular cancer, and portal vein thrombosis were excluded. Every patient had a blood sample taken for the platelet count, which was then forwarded to the hospital lab for analysis. The ratio of platelet count to spleen diameter was computed for each patient using the formula PSR=platelet count (N/mm3)/spleen diameter (mm). For esophageal varices, a PSR ratio of less than 0.909 was considered favorable. The diagnostic accuracy of the platelet count/spleen diameter ratio was computed and compared with the results of endoscopy. Results: PSR values with sensitivity of 87.50%, specificity of 89.32%, PPV of 88.42%, NPV of 88.46%, and diagnostic accuracy of 88.44% were used to identify the esophageal varices. Conclusion: According to our findings, the platelet count/spleen diameter ratio is a reliable indicator of whether EV is present or absent in individuals with hepatic cirrhosis.
Maqsood et al. (Wed,) studied this question.