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November 28, 2025Current Opinion in Nephrology & Hypertension0 citations

Ethical challenges in kidney transplantation

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AIAvantika IsraniUniversity of Arkansas Medical CenterAIAjay K. IsraniUniversity of MinnesotaJBJudith A. BensteinNew York University

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Abstract

Purpose of review This review provides a comprehensive examination of the current inequities and ethical challenges in kidney transplantation and highlights some of the most urgent issues related to organ allocation and emerging technologies. Recent findings Several recent news and media reports have significantly undermined public trust in the organ transplantation and allocation process. This review discusses some of these controversies and proposes strategies to restore confidence in the system. With advancements in gene editing, xenotransplantation is becoming a tangible reality, bringing forth new ethical challenges explored in this paper. Likewise, as artificial intelligence continues to permeate medicine and moves closer to integration within transplantation, proactive preparation and ethical foresight are essential. Summary In conclusion, we aim to draw attention to pressing ethical dilemmas in kidney transplantation and suggest actionable steps to restore trust.

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Israni et al. (2025) studied this question.

synapsesocial.com/papers/69402e042d562116f2904625https://doi.org/10.1097/mnh.0000000000001141
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