Weight-band-based simplification of oral allometric miltefosine dosing in paediatric patients with visceral leishmaniasis. | Synapse
January 25, 2026
Weight-band-based simplification of oral allometric miltefosine dosing in paediatric patients with visceral leishmaniasis.
Key Points
To evaluate a simplified weight-band-based dosing strategy for miltefosine in pediatric patients with visceral leishmaniasis.
Developed a weight-band-based dosing strategy for miltefosine.
Assessed pharmacokinetics to ensure satisfactory exposure levels in children.
Compared new dosing strategy with traditional allometric dosing.
The weight-band-based dosing provided satisfactory exposure levels.
It serves as a practical alternative to traditional dosing methods.
Abstract
Our simplified WB-based dosing strategy offers a practical alternative for allometric miltefosine dosing in children, yielding satisfactory exposure levels.