What question did this study set out to answer?

This research investigates how adenomyosis affects brain activity linked to pain and emotions.

February 2, 2026Annals of Medicine0 citationsOpen Access

Regional homogeneity alterations reflect pain and emotional dysregulation in adenomyosis

WWWenjiang WeiSecond Hospital of Shandong University YCYanying ChenSecond Hospital of Shandong University KHKelei HuaSecond Hospital of Shandong University

Key Points

This research investigates how adenomyosis affects brain activity linked to pain and emotions.
Analyzed intrinsic brain activity in regions related to pain and emotion
Conducted neuroimaging studies
Identified alterations in regional homogeneity
Alterations in brain activity correlate with chronic pain symptoms
Emotional dysregulation linked to brain dysfunction in adenomyosis

Abstract

AMD is characterized by altered intrinsic brain activity in pain- and emotion-related regions, supporting a central mechanism underlying chronic pain and affective symptoms. These findings provide neuroimaging evidence for AMD-related brain dysfunction. Longitudinal studies with larger cohorts and hormonal control are warranted to confirm these results and clarify causal relationships.

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Cite This Study

Wei et al. (Fri,) studied this question.

synapsesocial.com/papers/6980ff37c1c9540dea81206d https://doi.org/https://doi.org/10.1080/07853890.2026.2620857

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