Platinum-based phosphorescent lifetime probes for the visualisation of G-quadruplex DNA in cells

Key Points

• The study aims to visualize g-quadruplex DNA structures in cells using platinum-based phosphorescent probes.
• Developed platinum-based phosphorescent lifetime probes.
• Applied probes to cellular models to detect g-quadruplex DNA.
• Utilized imaging techniques to visualize the probes in live cells.
• Successfully visualized g-quadruplex DNA structures in cellular environments.
• Probes showed distinct lifetime characteristics when bound to g-quadruplexes.
• Demonstrated the biological relevance of g-quadruplex structures in cellular regulation.