Discovery of fluorescent properties in mitoxantrone hydrochloride injection for tracing: application for sentinel lymph node biopsy in breast cancer

Key Points

• The study aims to evaluate the effectiveness of mitoxantrone hydrochloride as a fluorescence tracer for sentinel lymph node biopsy in breast cancer.
• Assessment of mitoxantrone's fluorescence properties
• Comparison with established tracers like methylene blue and indocyanine green
• Evaluation of lymphatic specificity and visual clarity
• Mitoxantrone demonstrated clear fluorescence visibility.
• Combined advantages enhance accuracy of lymph node identification.
• Potential improvements in surgical practicality and outcomes were noted.