Establishment and validation of a novel risk stratification scale in adult IgA vasculitis nephritis: a cohort study based on a systematic review and meta-analysis

Key Points

• This research aims to create a risk stratification scale to identify adults with IgA vasculitis nephritis (IgAVN) at high risk for poor outcomes.
• Conducted a cohort study using a systematic review and meta-analysis approach.
• Developed a risk stratification scale based on clinical characteristics.
• Validated the scale's effectiveness in predicting outcomes.
• Identified specific risk factors associated with unfavorable outcomes.
• Demonstrated that the scale effectively categorizes patients by risk levels.
• Highlighted the potential for improving early clinical decision-making.