What question did this study set out to answer?

The research aims to establish a comprehensive database of biological variation for lung cancer biomarkers in elderly Asians.

February 14, 2026Open Access

Monthly Biological Variation of Five Lung Cancer Markers in Healthy Older Individuals: Evidence from Combined Prospective Cohort and Real-World Data Analyses

Key Points

The research aims to establish a comprehensive database of biological variation for lung cancer biomarkers in elderly Asians.
Combined prospective cohort and real-world data analyses
Monthly monitoring of five lung cancer biomarkers
Focus on healthy older individuals
Stable monthly variation of biomarkers was identified
Personalized reference control values (RCVs) could enhance clinical interpretation
Findings enable earlier therapeutic interventions for aging individuals

Abstract

This study establishes the first comprehensive BV database for lung cancer biomarkers in elderly Asians. Stable monthly variation enables flexible monitoring protocols. Our findings support implementing personalized RCVs for clinical interpretation and facilitate earlier therapeutic interventions for aging individuals.

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Cite This Study

Han et al. (Thu,) studied this question.

synapsesocial.com/papers/699012032ccff479cfe58b99 https://doi.org/https://doi.org/10.3343/alm.2025.0528

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