We report a case with clinical side effects related to extravasation of 177 Lu-PSMA (estimated activity of 2.25 GBq) after administration via the cubital vein. After initial cooling (±10 min), the patient was asked to elevate and mobilize the arm. Five weeks post-injection (p.i.), the patient reported localized pruritus. An erythematosqualous plaque with lichenification was observed. At 9 weeks p.i., a slight inflammatory hyperpigmentation remained; all other symptoms had disappeared.
Corveleyn et al. (Mon,) studied this question.