This longitudinal, randomized, parallel-design clinical trial aimed to evaluate the long-term effectiveness of different in-office treatments for dentin hypersensitivity (DH) over a 6-month period. A total of 192 teeth presenting DH associated with root surface exposure were treated with one of four desensitizing agents: fluoride varnish (Duraphat – FLU, active control), bioactive ceramic solution (Biosilicate – BIOS), universal self-etching adhesive (Single Bond Universal – SBU), and a bioactive, photoactivated varnish containing PRG fillers (SPRG). DH was assessed using a visual analogue scale (VAS) to analyse intensity of sensitivity and a computerized visual scale (CoVAS) to observe the time course of sensibility at baseline, 7, 15, 30 days and 6 months post-treatment. Comparisons between groups were conducted using Fisher’s exact test for qualitative variables and analysis of variance (ANOVA) for quantitative variables. Longitudinal outcomes (VAS and CoVAS) were evaluated using linear mixed-effects models, with post hoc comparisons performed using orthogonal contrasts. Statistical differences were found for VAS analysis (p 0.05). In conclusion, root exposure height and the presence of an antagonist tooth may influence the initial intensity of DH. All treatments reduced DH over 6 months. Only bioactive resin varnish maintained the same reaction time in all periods. Universal adhesive system had slowed pain reaction time compared to conventional fluoride varnish.
Ramos et al. (Tue,) studied this question.