What question did this study set out to answer?

The central aim is to develop a biosensor for the detection of thyroid nodules using phase-change materials.

February 21, 2026Open Access

Chemical-enhanced thyroid cell detection using photonic crystal biosensors with phase-change materials

WNWalaa M. NoumanBenha University FSFatma A. SayedBeni-Suef University AAArafa H. AlyBeni-Suef University

Key Points

The central aim is to develop a biosensor for the detection of thyroid nodules using phase-change materials.
Developed a one-dimensional defective photonic crystal (1D-DPC) biosensor
Utilized the phase-change material Ge2Sb2Te5 (GST)
Focused on detection in the visible light range.
Demonstrated effective label-free detection of thyroid nodules using the biosensor
Achieved promising sensitivity and specificity in visible light detection.

Abstract

This study proposes a one-dimensional defective photonic crystal (1D-DPC) biosensor based on the phase-change material Ge 2 Sb 2 Te 5 (GST) for label-free detection of thyroid nodules in the visible range.

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