Formulation-dependent dissolution and bioaccessibility of curcuminoids and (S)-ar-turmerone from eight commercial turmeric extract- and curcumin-containing dietary supplements.

Key Points

• This research aims to evaluate the dissolution and bioaccessibility of curcuminoids and (S)-ar-turmerone in dietary supplements.
• Examined eight commercial turmeric extract and curcumin dietary supplements.
• Performed in vitro dissolution tests to assess release rates.
• Analyzed differences in bioavailability among various formulations.
• Found significant variations in dissolution and bioaccessibility among the tested supplements.
• Noted that superior in vitro release does not necessarily ensure enhanced systemic exposure.
• Highlighted the importance of scrutinizing bioavailability claims on product labels.