Export Objective: Central venous catheter-related bloodstream infection is a leading cause of hospitalization and death in patients treated with chronic hemodialysis. Infection is second only to cardiovascular disease as a cause of death in end-stage renal disease. Septicemia accounts for more than 75% of infection-related death. The aim of this study was to identify the incidence of catheter-related bacteremia in a hemodialysis patient, types of infection, the most common organism, and the response to treatment with antibiotics. Methods: Three hundred patients with end stage renal disease in whom tunneled and non-tunneled catheters used for hemodialysis in the Dialysis Center of Alkadhumain Medical City from February 2020 to February 2021. Only 122 of them gave signs and symptoms of catheter related infection, blood culture, catheter tip culture, white blood cell (neutrophile, lymphocyte), haemoglobin, blood urea, serum creatinine, random blood sugar, serum albumin, chest X-ray and general urine examination were evaluated in these patients. Results: The most common bacteria identified in blood culture was Staphylococcus epidermidis, which was presented in 30 (24.5%) patients, Staphylococcus aureus which were presented in 12 (9.8%) patients. This followed by methicillin resistance Staphylococcus aureus and proteus mirabilis, which were found in 9 (7.3%) patients for each bacterium. Klebsiella pneumonia was presented in 8 (6.2%) patients. There were 42 (34.4%) patients have negative results on blood culture. Positive blood culture was associated with lower duration of symptoms (P-value =0.043), with higher white blood cell and neutrophilia (P-value <0.0001), and with lower serum creatinine and serum albumin (P-value =0.01 and 0.008, respectively). The catheter tip culture was done for 58 (47.5%) patients, it revealed that Pseudomonas aeruginosa was the most common bacteria, identified in 14 (11.4%) patients. Methicillin sensitive Staphylococcus aureus was presented in 12 (9.8%). Methicillin resistant Staphylococcus aureus was presented in 9 (7.3%) patients. Negative results were observed in 12 (9.8%) patients. Conclusions: The blood culture showed nearly 2 third of patients have a positive culture. The most common bacteria identified in blood culture was Staphylococcus epidermidis, while the Staphylococcus aureus was reported in 16% of patients. Positive catheter tip culture was observed in 2 third of patients. The catheter tip culture showed that Pseudomonas aeruginosa was the most common bacteria identified.
Manuti et al. (Fri,) studied this question.